![]() The live-action sequences are set outside Frank's body while the animated sequences are set inside his body, which is depicted as a city inhabited by anthropomorphic parameciums. Featuring the voices of Chris Rock, Laurence Fishburne, David Hyde Pierce, Brandy Norwood and William Shatner alongside live actors such as Bill Murray, Molly Shannon and Chris Elliott, the film centers on Frank DeTorre, a slovenly zookeeper who contracts a deadly virus known as Thrax. ![]() Osmosis Jones is a 2001 American live-action/animated buddy cop action comedy film directed by Piet Kroon and Tom Sito handling the animation and the Farrelly brothers directing the live-action sequences.
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